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Felty’s syndrome

A disorder characterized by rheumatoid arthritis, an enlarged spleen, a decreased white blood cell count, and recurrent infection.

Causes of Felty’s syndrome

The cause of Felty’s syndrome is unknown. It is a variant of rheumatoid arthritis and is more common in people who have had rheumatoid arthritis for a long time. People with this syndrome suffer from an increased incidence of infection associated with the low white blood cell count.

Symptoms of Felty’s syndrome

  • general feeling of discomfort
  • fatigue
  • loss of appetite
  • weight loss
  • pale color
  • joint swelling, stiffness, pain, and deformity
  • recurrent infections
  • eye burning, and/or discharge

Diagnosis of Felty’s syndrome

A physical examination shows an enlarged spleen, and may also show an enlarged liver or enlarged lymph nodes. Joint findings are typical of rheumatoid arthritis.

A CBC may show decreased neutrophil count.

Treatment  of Felty’s syndrome

People with this syndrome are usually already under treatment for rheumatoid arthritis.

Splenectomy (removal of the spleen) may improve the white cell count and the susceptibility to infections.


 Felty's Syndrome Picture

This web site is intended for your own informational purposes only. No person or entity associated with this web site purports to be engaging in the practice of medicine through this medium. The information you receive is not intended as a substitute for the advice of a physician or other health care professional. If you have an illness or medical problem, contact your health care provider.


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