About Us

Complete List of our  Arthritis Topics

Arthritis News


Content edited by and some written by Rusty Ford


We respect your privacy read our full Privacy Policy
Terms of service

This site does not use cookies




Causes Symptoms Diagnosis




Gout Diet

Causes of Gout

Genetics plays a roll in causing gout. Three genes called SLC2A9, SLC22A12 and ABCG2 have been found to commonly be associated with gout, and variations in them can approximately double the risk

There are many who think that there are diet may account for about 12% of gout including the consumption of alcohol, fructose-sweetened drinks, meat, and seafood.

Various medical problems can play a role in developing gout. . People with the following conditions commonly see a higher than normal rate of developing gout:: polycythemia, lead poisoning, renal failure, hemolytic anemia, psoriasis, and solid organ transplants. People who are obese are also at a higher risk of developing gout.

Certain medicines diuretics have been associated with attacks of gout. Niacin, aspirin and some immunosuppressant's have also been associated with gout.

As a result of high levels of uric acid in the blood, needle-like urate crystals gradually accumulate in the joints. Urate crystals may be present in the joint for a long time without causing symptoms. Infection, injury to the joint, surgery, drinking too much, or eating the wrong kinds of foods may suddenly bring on the symptoms, which include pain, tenderness, redness, warmth, and swelling of the joint. In many cases, the gout attack begins in the middle of the night. The pain is often so excruciating that the sufferer cannot bear weight on the joint or tolerate the pressure of bedcovers. The inflamed skin over the joint may be red, shiny, and dry, and the inflammation may be accompanied by a mild fever. These symptoms may go away in about a week and disappear for months or years at a time. However, over the course of time, attacks of gout recur more and more frequently, last longer, and affect more joints. Eventually, stone-like deposits known as tophi may build up in the joints, ligaments, and tendons, leading to permanent joint deformity and decreased motion. (In addition to causing the tophi associated with gout, hyperuricemia can also cause kidney stones, also called renal calculi or uroliths.)

Gout Causes - Demographics

Gout affects an estimated one million Americans. It most commonly afflicts men (800,000 men versus 200,000 women). Uric-acid levels tend to increase in men at puberty, and, because it takes 20 years of hyperuricemia to cause gout symptoms, men commonly develop gout in their late 30s or early 40s. Women more typically develop gout later in life, starting in their 60s. According to some medical experts, estrogen protects against hyperuricemia, and when estrogen levels fall during menopause, urate crystals can begin to build up in the joints. Excess body weight, regular excessive alcohol intake, the use of blood pressure medications called diuretics, and high levels of certain fatty substances in the blood (serum triglycerides) associated with an increased risk of heart disease can all increase a person's risk of developing gout.

The risk is greater in men, postmenopausal women, and people who use alcohol.


Gout description and picture






This web site is intended for your own informational purposes only. No person or entity associated with this web site purports to be engaging in the practice of medicine through this medium. The information you receive is not intended as a substitute for the advice of a physician or other health care professional. If you have an illness or medical problem, contact your health care provider.

Arthritis can develop as a result of an infection. For example, bacteria that cause gonorrhea or Lyme disease can cause arthritis. Infectious arthritis can cause serious damage, but usually clears up completely with antibiotics. Scleroderma is a systemic disease that involves the skin, but may include problems with blood vessels, joints, and internal organs. Fibromyalgia syndrome is soft-tissue rheumatism that doesn't lead to joint deformity, but affects an estimated 5 million Americans, mostly women. The approximate number of cases in the United States of some common forms of arthritis. is an informational out reach of the Consumer Health Information Network. It is our goal to provide up to date information about arthritis and other inflammatory and bone conditions in a easy to understand format.

Where we get our information.

Most of the information in the site is compiled by editors from information provided by the National Institutes of Health. We are in the process of updating our pages. In the past we have not made reference to the source for information provide by our editors. In the next few weeks we hope to have all our pages marked as to the source.

We have included information from the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Pages that uses information from this source are so acknowledged.

We have contributing authors that send information. Where information is provided by an outside author it is acknowledged by a byline under the title.

Updates of Pages.

Not all of our pages have a date as to the last update. We are in the processes of reviewing all our pages and as we do we include a reference as to when the page was updated. This web site was first published in January of 2003. All pages in the site were created at sometime during or after that time.