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Plaquenil

Complete list of drugs used to treat arthritis.

Plaquenil is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this Plaquenil be used?

Plaquenil comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1-2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. For treatment of acute attacks of malaria in adults, four tablets are usually taken right away, followed by two tablets 6-8 hours later and then two tablets on each of the next 2 days.

For prevention or treatment of malaria in infants and children, the amount of Plaquenil is based on the child's weight. Your doctor will calculate this amount and tell you how much Plaquenil your child should receive.

For lupus erythematosus, one or two tablets are usually taken once or twice daily. For rheumatoid arthritis, one to three tablets are usually taken once a day.

Plaquenil can be taken with a glass of milk or a meal to decrease stomach upset. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Plaquenil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are taking Plaquenil for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking Plaquenil without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking Plaquenil.

Other uses for Plaquenil

Plaquenil is used occasionally to treat porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow?

Before taking Plaquenil,

  • tell your doctor and pharmacist if you are allergic to Plaquenil, chloroquine (Aralen), primaquine, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially acetaminophen (Tylenol, others), digoxin (Lanoxin), iron-containing medications (including multivitamins), isoniazid (Nydrazid), methotrexate (Rheumatrex), niacin, rifampin (Rifadin, Rimactane), and vitamins and herbal products.
  • tell your doctor if you have or have ever had liver disease, psoriasis, porphyria or other blood disorders, G-6-PD deficiency, dermatitis (skin inflammations), or if you drink large amounts of alcohol.
  • tell your doctor if you have ever had vision changes while taking Plaquenil, chloroquine (Aralen), or primaquine.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Plaquenil, call your doctor.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can Plaquenil cause?

Although side effects from Plaquenil are not common, they can occur.Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • dizziness
  • loss of appetite
  • upset stomach
  • diarrhea
  • stomach pain
  • vomiting
  • skin rash

If you experience any of the following symptoms, call your doctor immediately:

  • reading or seeing difficulties (words, letters, or parts of objects missing)
  • sensitivity to light
  • blurred distance vision
  • seeing light flashes or streaks
  • difficulty hearing
  • ringing in ears
  • muscle weakness
  • bleeding or bruising of the skin
  • bleaching or loss of hair
  • mood or mental changes
  • irregular heartbeat
  • drowsiness
  • convulsions

What storage conditions are needed for this Plaquenil?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Children can be especially sensitive to an overdose, so keep the medication out of the reach of children. Children should not take Plaquenil for long-term therapy.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to Plaquenil.

If you are taking Plaquenil for a long period of time, your doctor will recommend frequent eye exams. It is very important that you keep these appointments. Plaquenil can cause serious vision problems. If you experience any changes in vision, stop taking Plaquenil and call your doctor immediately.

 
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This web site is intended for your own informational purposes only. No person or entity associated with this web site purports to be engaging in the practice of medicine through this medium. The information you receive is not intended as a substitute for the advice of a physician or other health care professional. If you have an illness or medical problem, contact your health care provider.

07/09/2008

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